Performance of the Automated COBAS AmpliPrep/COBAS TaqMan HIV-1 Test on a Genetically Diverse Panel of Specimens from China: Comparison to the COBAS Amplicor HIV-1 Monitor Test, v1.5

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Performance of the automated COBAS AmpliPrep/COBAS TaqMan HIV-1 test on a genetically diverse panel of specimens from China: comparison to the COBAS amplicor HIV-1 monitor test, v1.5.

OBJECTIVES To investigate the impact of genetically diverse HIV samples from China on the performance of the automated COBAS(R) AmpliPrep/COBAS TaqMan(R) HIV-1 Test (CAP/CTM). METHODS 185 samples from untreated HIV-1-infected patients were used to assess the performance of the CAP/CTM Test and COBAS Amplicor HIV-1 Monitor Test, v1.5 (Cobas). RESULTS A comparison of the qualitative results o...

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Comparison of the Abbott realtime human immunodeficiency virus type 1 (HIV-1) assay to the Cobas AmpliPrep/Cobas TaqMan HIV-1 test: workflow, reliability, and direct costs.

The Abbott RealTime human immunodeficiency virus type 1 (HIV-1) assay (ART) and the Cobas AmpliPrep/Cobas TaqMan HIV-1 test (CTM) are commercially available assays for quantification of HIV-1 RNA in plasma. We evaluated performance characteristics, workflow, throughput, reliability, and direct costs of these assays. Both assays yielded good correlation of quantitative results (r = 0.95) among c...

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ژورنال

عنوان ژورنال: Intervirology

سال: 2010

ISSN: 1423-0100,0300-5526

DOI: 10.1159/000299064